Amphotericin B
Description
Amphotericin B is a polyene macrolide antifungal antibiotic produced by Streptomyces nodosus. It binds to ergosterol in fungal cell membranes, forming pores that cause leakage of cellular components and cell death. In plant tissue culture, amphotericin B is applied to suppress fungal contamination without significant toxicity to plant tissues when used at appropriate concentrations.
Technical info
Components
- Synonyms: Fungizone, Amphotericin
- Chemical formula: C₄₇H₇₃NO₁₇
- Molecular weight: 924.08 g/mol
- CAS number: 1397-89-3
- Purity: ≥80% (potency)
- Appearance: Yellow to orange crystalline powder
- Solubility: Insoluble in water; soluble in DMSO, DMF, and deoxycholate formulations
Storage conditions
- Store at −20 °C
- Protect from light and moisture
Applications
- Antifungal agent in plant tissue culture
- Control of yeast and mold contamination
- Widely used in microbiology and biotechnology research
Hazard classification (GHS)
- H302: Harmful if swallowed
- H315: Causes skin irritation
- H319: Causes serious eye irritation
Precautionary statements
- P280: Wear protective gloves/protective clothing/eye protection/face protection
- P301+P312: IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell
- P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes
MSDS
MSDS
Certificate of Analysis
Certificate of Analysis
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PEPP is designed by Plant Biotechnologies using natural plant extracts to protect plant from bacterial, fungal without using antibiotics